• Clinical and Biochemical Outcomes of High-Risk Prostate Cancer Patients treated with Third Generation Prostate Cryoablation- with and without neoadjuvant hormones

  S Wenske, PJ Cheetham, AE Katz
  Journal of Analytical Oncology 2013 (Vol 2) No 2 p120-7

• Tubulin targeted agents including docetaxol and cabazitaxel

  PJ Cheetham and DP Petrylak
  The Cancer Journal. Special Edition on New Agents for Prostate Cancer 2013 19 (1) p59-65

• Update on Diet and Nutrition in Prostate Cancer

  PJ Cheetham
  AUA news December 2012 edition pages 11-12 Guest Editor Gopal Badlani.

• Abiraterone and increased survival in metastatic prostate cancer

  PJ Cheetham and DP Petrylak
  Eur Urol. 2012 Apr;61(4):850

• Alpha Particles as Alpha-pharmaceuticals in the Treatment of Bone Metastases: Mechanism of Action of Alpharadin and Radiation Protection. Review Article

  PJ Cheetham and DP Petrylak
  Oncology 2012 Apr;26(4):330-7, 341.

• Adjuvant and Neoadjuvant Chemotherapy for Bladder Cancer: Current Concepts

  PJ Cheetham and DP Petrylak
  Accepted for publication in AUA news December 2011. Published in May 2012 p31

• Diet and Prostate Cancer: A Holistic Approach To Management

  Monographic: Clinically localized prostate cancer: current approaches and options
  PJ Cheetham and Aaron Katz.
  Arch Esp Urol. 2011 Oct;64(8):720-34

• Vitamin D Deficiency In The Urologic Population: A Single-Center Analysis

  MS Pitman, PJ Cheetham, GW Hruby AE Katz.
  Accepted for publication Journal of Urology April 2011.

• Acupuncture for the Treatment of Hot Flashes in Men with Advanced Prostate Cancer

  J Capodice, PJ Cheetham, MC Benson, JM McKiernan, AEKatz.
  International Journal of Clinical Medicine 2011;2(1):51-55.

• Indications and Trends in Pelvic Lymph Node Dissection for Prostate Cancer

  B Djavan, AKazzazi, L Dulabon, S Momtahen, S Dianat, M Sand, P Cheetham, G Janetschek, HLepor, MGraefen.
  Accepted European Urology March 2011.

• The Legacy of Testosterone in Prostate Cancer: The Bethesda Consensus

  R Djavan, M Garnick, J Eastham, L Gomella, S Taneja, S. Dianat, A Kazzazi, N Shore, P Abrahamson, PJ Cheetham, JW Moul, H Lepor, D Crawford.
  Submitted to Journal of Clinical Oncology March 2011.

• Does the presence of robotic surgery affect demographics in patients choosing to undergo radical prostatectomy? A multi-center contemporary analysis.

  PJ Cheetham, DJ Lee, A Rose-Morris, SF. Brewster, KK. Badani
  Journal of Robotic Surgery 2010;4(3):155-160.

• Gleason score concordance on biopsy confirmed prostate cancer: Is pathologic re-evaluation necessary prior to radical prostatectomy?

  M Truesdale: PJ Cheetham, A Turk, S Sartori, G Hruby, E Dinnen; MC Benson, K Badani.
  BJU Int. 2010 Sep 14. doi: 10.1111/j.1464-410X.2010.09570.x. [Epub ahead of print]

• Longterm Cancer-Specific and Overall Survival for Men followed more than 10 years after Primary and Salvage Cryoablation of the Prostate.

  P Cheetham, M Truesdale, S Chaudhury, S Wenske, GW Hruby, A Katz.
  J Endourol. 2010 Jul;24(7):1123-9.

• Predictors of Early Urinary Continence after Robotic Prostatectomy

  DJ Lee, PJ Cheetham, KK Badani.
  Can J Urol 2010; 17(3): 5200-5.

• Clinical and Biochemical Outcomes of High-Risk Prostate Cancer Patients treated with Third Generation Prostate Cryoablation- with and without neoadjuvant hormone therapy.

  S Wenske, PJ Cheetham, S Stevenson, M Truesdale, G Hruby, AE Katz.
  Accepted Journal of Clinical Oncology. In Press.

• Assessment of Lymph Node Yield Following Pelvic Lymph Node Dissection in Men with Prostate Cancer: A Comparison between Robotic-Assisted Radical Prostatectomy and Open Radical Prostatectomy in the Modern Era.

  MD Truesdale, DJ Lee, PJ Cheetham, GW Hruby, AT Turk, KK Badani.
  J Endourol. 2010 Jul;24(7):1055-60.

• Use Of A Flexible Co2 Laser Fiber For Precise Dissection Of The Neurovascular Bundle During Robotic Assisted Laparoscopic Prostatectomy.

  PJ Cheetham, MD Truesdale, DJ Lee, JM Landman, KK Badani.
  J Endourol. 2010 Jul;24(7):1091-6.

• An Evaluation Of Patient Selection Criteria On Predicting Progression-Free Survival Following Primary Focal Unilateral Nerve-Sparing Cryoablation For Prostate Cancer.

  M Truesdale, PJ Cheetham, G Hruby, A Conforto, A Cooper, A Katz.
  Accepted Journal of Cancer Jan 2010. In Press.

• Penile rehabilitation protocol after robotic radical prostatectomy: assessment of compliance of phosphodiesterase-5 inhibitor therapy and effect on early potency.

  DJ Lee, PJ Cheetham, KK Badani.
  Accepted Online Early - BJU-2009-0561 Aug [Epub ahead of print].

• Evaluation of Preoperative Planning Criteria To Determine Oncologic Safety In Men Who Undergo A Lateral Prostatic Fascia Nerve Sparing Procedure During Robotic Radical Prostatectomy.

  PJ Cheetham, DJ Lee, KK Badani.
  J Urol 2009:181(4):363.

• A Management Algorithm for Hematospermia.

  M Aslam, PJ Cheetham, MAW Miller.
  Nat. Rev. Urol 2009;6:398–402.

• Prostate Cryoablation Before and After Transurethral Resection of the Prostate: The Columbia University Experience.

  PJ Cheetham, S Stevenson, Z Saeed, AE Katz.
  Submitted to Journal of Urology August 2010.

• Prostate Cryoablation Before and After Transurethral Resection of the Prostate: The Columbia University Experience.

  PJ Cheetham, S Stevenson, Z Saeed, AE Katz.
  Submitted to American Journal of Transplantation August 2010.

• Peri-Catheter Pad Use Immediately Post-Op As A Novel Predictor Of Early Return Of Urinary Continence After Robotic Prostatectomy.

  PJ Cheetham, M. Truesdale, J Landman, K Badani.
  Submitted Journal of Urology - under review.

• The History of Surgical Robotics.

  PJ Cheetham, KK Badani.
  Accepted publication De Historia Urologiaeae Europaeae EAU - Sept. 2009.

• Management of Urinary Tract Infection in Adults.

  PJ Cheetham.
  BMJ 2006;9:774-791.

• A Questionnaire Study Assessing Current Attitudes of Doctors, Medical Students and Patients Views of the White Coat, with a Review of the History of the White Coat.

  PJ Cheetham, S Mc Donnell, SF Brewster.
  BMJ 2006.

• Attitudes and use of alternative therapies in UK prostate cancer patients – isn’t it time we were in the know?

  PJ Cheetham, K Le Monnier, SF Brewster.
  Prostate Cancer and Prostatic Diseases 2001; 4, 235-241.

• Case report on Ganglioneuroma.

  PJ Cheetham, O Espinota, DC Cranston.
  Online BJUI webcasts.

• A 23-year review of the management of acute retention of urine: progressing or regressing?

  P Modi, J Pleat, PJ Cheetham, J Senior, R Johan & G Fellows.
  Ann R Coll Surg Engl 2000; 82:333-335.

• A retrospective study of bowel, bladder and sexual function in patients who have had an ileoanal pouch – lessons learned from 100 cases.

  PJ Cheetham & WH Thomson.
  Br J Surgery.

• Identification of kit-positive cells in the human detrusor.

  PJ Cheetham, J Reynard, AF Brading.

• The inhibitory effect of erythromycin lactobionate on the normal and neuropathic human detrusor.

  PJ Cheetham, P Guy, J Reynard, AF Brading.

AHCC (Active Hexose Correlated Compound)

Active Hexose Correlated Compound (AHCC) is one the world’s most researched natural immune-modulating compounds. Derived from mycelia (roots) of hybridized Lentinula edodes shiitake mushrooms, AHCC is very rich in acetylated alpha-glucans – a type of carbohydrate shown to modulate the immune system. Unlike other glucan-rich compounds, AHCC also has very low molecular weight of just 5000 Daltons, making it highly absorbable in the body.

AHCC is supported by 30 studies published in PubMed-referenced journals (reputable peer-reviewed publications whose scientific integrity is validated by the National Institutes of Health). Numerous human clinical studies show that AHCC increases the activity of important white blood cells (including Natural Killer Cells, T-Cell and Dendritic Cells) responsible for helping the body rid itself of abnormal and tumorous cells. AHCC has also been shown to help down-regulate an overactive immune system (helping support the body’s normal response to inflammation) so it functions as an "immune regulator" – not just a "booster".

AHCC is used in over 1000 clinics in Japan, Asia and the U.S. as a complementary immunotherapy for cancer patients, people with viral and non-viral hepatitis and immune-compromised individuals, including post-surgical patient and the elderly whose immune systems deteriorate with age. Importantly, AHCC has an excellent safety profile supported by strong data and having a long history of use. References to all AHCC studies can be found at www.AHCCresearch.com.

Broccoli seed extract

According to significant clinical evidence, diets rich in broccoli have been shown to help reduce the risk of many forms of cancer. Possessing anti-inflammatory properties, broccoli has also been found to promote the reduction of PSA levels.

Daily men's multivitamins

In addition to taking supplements, taking a daily multivitamin filled with essential vitamins and minerals is also necessary to maintain overall health.

Flaxseed

Flaxseed contains Omega-3 fatty acids and has outstanding benefits on the human body. The lignans in flaxseed may provide some protection against cancers that are sensitive to hormones such as breast and prostate. Lignins are phytoestrogrens- active substances derived from plants. Phytoestrogrens can help balance hormone levels by blocking enzymes involved in hormone metabolism. They can also interfere with or stop the growth and spread of tumor cells. Results have shown that 25 men with prostate cancer who took flaxseed had significantly reduced serum testosterone, slower growth rate of cancer cells, and increased death rate of cancer cells.

Lycopene

Lycopene is what gives tomatoes, watermelon, pink grapefruit, apricots and other red fruits and vegetables their red color. This pigment acts as an antioxidant in the body, protecting cells against damage from the free radicals formed when body cells burn oxygen for energy. A number of studies have demonstrated that men who get more lycopene in their diet have less risk of prostate cancer and an increase in energy. Lycopene is better absorbed by the body when it is consumed in cooked tomato products, rather than fresh tomatoes.

Modified citrus pectin (MCP)

Derived from the pits of citrus fruits, Modified Citrus Pectin (MCP) promotes optimal cellular health. Scientific research has also shown that MCP can support prostate and breast health. Unlike regular pectin, MCP is easily absorbed in the bloodstream. When absorbed, MCP can bind to and block large amounts of harmful proteins called Galectin-3, which are found in abnormal cell division. Therefore, MCP can sustain cellular growth and proliferation.

Omega 3 Fish Oil

Omega 3 fatty acids in fish oil provide unlimited health benefits. Since they are not naturally present in the body, scientific research has shown the necessity of these acids, particularly for the sustenance of the eye, brain, heart and kidney. In addition, growing evidence shows that Omega 3 fish oil can prevent the growth of certain cancers, as it stops the alteration from a normal cell to a cancerous mass.

Pomegranate

There are a multitude of recent studies showing that the pomegranate contains compounds which may have protective effects against prostate cancer. These antioxidant compounds called polyphenols have been shown to be capable of stopping the spread of cancer by killing off infected cells.

Vitamin D3

Vitamin D3 plays a key role in overall health. Stored in the body’s soft tissue, it maintains a strong immune system, supports bone health and protects against muscle weakness. Since it promotes a healthy immune function, vitamin D3 can also lower the risk of certain cancers, including colon, breast and prostate cancers.

Zyflamend

Zyflamend is an anti-inflammatory herbal supplement, which promotes a healthy inflammation response as well as normal cellular and joint function. Clinical studies show that this product can prevent certain cancers by reducing the growth of abnormal cells.

Testing / Screening

What test should you do / follow up with?

• If PSA is elevated, repeat the PSA test to check its elevation on a second reading.
• Examine the prostate - the digital rectal exam - does it feel suspicious, enlarged or hard?
• Urine prostate cancer gene test - called the PCA3 test.
• Consider doing a prostate biopsy.

Helpful Nutrition

Drink Green Tea

Green tea plays a major role in oriental diet, which may explain low risk of prostate cancer in Japanese men. It contains polyphenolic compounds, which have been suggested to decrease risk and slow progression of prostate cancer. In addition, green tea contains a very potent antioxidant EGCG – epigallocethecin-3-gallate. Studies have shown a significant reduction in incidence of prostate cancer in men with precancerous changes (high grade PIN) who drink green tea.

Drink Pinot Noir

A high concentration of a protective compound called resveratrol is found in red wine, particularly Pinot Noir. Resveratrol, a powerful antioxidant found in wine, grapes and berries, can slow the growth of prostate tumors. Researchers at the University of Alabama discovered that mice that consumed resveratrol were significantly less likely to develop prostate cancer. Red wine has about 1.5 to 3 milligrams of resveratrol per liter (a liter is almost 34 ounces).

Drink Pomegranate Juice

Deeply colored red and purple fruits, such as pomegranates, are rich in ellagitannins and other compounds, which have anti-oxidant and anti-inflammatory actions in the body. Ruby red pomegranate seeds (the arils) contain numerous chemicals that have all been found to inhibit cell growth spurred by testosterone which usually drives prostate cancer. One study found that men who drank pomegranate juice after being diagnosed with prostate cancer prolonged PSA doubling time significantly.

Reduce the amount of red meat in your diet because...

There is increasing evidence that heterocyclic amines found in cooked meat are crucial carcinogens that have been implicated in the development of a number of cancers. Particularly harmful compounds are:

• Charred (BBQued) meats creating harmful poly-aromatic hydrocarbons
• Cured meats which contain cancer-encouraging nitrates

These compounds act on DNA causing subsequent instability and mutagenesis. More than 22 studies on diet and prostate cancer have demonstrated that the more red meat a man eats, the higher his risk of developing the disease.

Read this CNN Health article for more information.

Pan-Fried Meat Ups Prostate Cancer Risk

Like your meat sizzling in a pan? You may want to reconsider: A new study finds that pan-fried meat may be associated with an increased risk of advanced prostate cancer.

Announced on Thursday August 16 2012, the study found that men who ate more than 1.5 servings of pan-fried red meat per week were 30 percent more likely to have advanced prostate cancer than those who rarely ate it.

Also, men who ate more than 2.5 servings of red meat cooked by any high-temperature method, such as broiling and grilling, had a 40 percent increased risk of advanced prostate cancer compared with men who rarely ate meat cooked at high temperatures.

To reach their findings, study researcher Mariana Stern and her team surveyed men in California, examining the red meat-eating habits of nearly 1,900 prostate cancer patients and 1,096 men without prostate cancer.

Researchers say more work needs to be done before making dietary recommendations but advise men to limit their intake of pan-fried meat, "to be on the safer side," said Stern, an epidemiologist at the University of Southern California's Keck School of Medicine. The findings were published online in the journal Carcinogenesis.

Cooking Method Matters

Red meat cooked at high temperature is thought to increase the risk of advanced prostate cancer due to compounds called polycyclic aromatic hydrocarbon (PAHs) and heterocyclic amines (HCAs). PAHs form when fat is cooked at high temperatures - when rising smoke from dripping fat leave PAHs deposits on the meat. HCAs form when sugars and other molecules in the meat are heated - and higher temperatures and longer cooking times cause more HCA to form, the researchers noted. Previous studies have yielded mixed results - some have shown a link between eating red meat and prostate cancer, and others found no increased cancer risk.

Take nutritional supplements

• AHCC (active hexose correlated compound)
• Broccoli Seed Extract
• Daily Men's Multivitamins
• Lycopene
• Pomegranate
• Vitamin D3
• Omega-3 Fish Oil
• Modified Citrus Pectin (MCP)
• Zyflamend

Nearly 11 million women in the United States are given antibiotics for urinary tract infections (UTI). Affecting four in five women, UTIs are the second most common reason for absenteeism at work and 80 percent of all women will experience a UTI in their lifetime. Recurrent UTIs can be especially harmful for women if they find themselves on multiple courses of antibiotics year-round.

Antibiotics can also increase a woman's odds of additional infections, antibiotic resistance and yeast infections – all of which can erode the immune system. Prevention of UTIs is often your best course of action – Try to incorporate these natural solutions into your daily routine:

• Cranberry Juice or Extract (cranberry supplements are preferred over juice that tends to have excess sugar content)
• AHCC (Japanese mushroom extract to boost immune system – available in powder or pill form): www.AHCCresearch.org
• Vitamin D3 (to boost immune system)
• Japanese Green Tea
• Drink non-carbonated drinks (water is best)

Bad bladder irritants for UTI include (stay away from these items):

• Carbonated Drinks (including sparkling water)
• Coffee (including decaffeinated coffee)
• Alcohol
• Tomatoes
• Citrus Fruits (ie: Grapefruit, Lemons, etc.)
• Chocolate

PROSTATE RELATED ISSUES

• Elevated PSA
• BPH (benign prostate enlargement)
• Prostatitis
• Localized Prostate Cancer
• Advanced Prostate Cancer
• Minimally Invasive Treatments for Prostate Cancer
• Prostate Cancer prevention strategies
• Holistic / Integrative Urology Issues

FEMALE UROLOGY ISSUES

• Recurrent Urinary Tract Infections (UTIs)
• Pelvic pain related to the female urinary tract
• Urinary Incontinence (male and female)
• Stress Incontinence procedures
• Interstitial Cystitis

BLOOD IN THE URINE

• Gross hematuria (blood in the urine)
• Microscopic hematuria

UROLOGIC CANCERS

• Kidney Cancer
• Bladder Cancer
• Prostate Cancer
• Testicular Cancer
• Urethral Cancer

STONES & CYSTS

• Kidney Stones
• Kidney cysts
• Bladder stones

URINARY SYMPTOMS

• Painful urination
• Recurrent UTIs
• Pyelonephritis
• Urinary urgency
• Overactive Bladder (OAB)
• Issues with Poor Urinary flow
• Urethral stricture disease
• Urinary Retention

MALE GENITAL ISSUES

• Testicular swellings
• Epididymal cysts
• Hydrocele
• Vasectomy Counseling
• Erectile dysfunction
• Low testosterone
• Male Infertility

NEUROLOGY PROBLEMS AFFECTING THE BLADDER

• Bladder Problems relating to Multiple Sclerosis
• Bladder Problems relating to Parkinson's Disease
• Bladder Problems relating to Diabetes
• Bladder problems relating Stroke, Brain or Spinal Cord Injury
• Bladder Abnormalites detected on Urodynamic Testing
• Botox injections for the bladder